"Let's Clear the Air" - UV-Clear DATA

Referenced Studies

"The safety of 222 nm was also studied. We detected changes to the mechanical properties of the stratum corneum of human skins when the 222 nm accumulative exposure exceeded 50 J/cm2." (https://www.nature.com/articles/s41598-022-09930-2)
"We compare the emerging 222-nm far UVC and 277-nm UVC LED disinfection modules with the traditional UVC mercury lamp emitting at 254 nm to understand their effects on human retinal cell line ARPE-19 and HEK-A keratinocytes. Cells illuminated with 222-nm far UVC survived while those treated with 254-nm and 277-nm wavelengths underwent apoptosis via JNK/ATF2 pathway. However, cells exposed to 222-nm far UVC presented the highest degree of DNA damage as evidenced by yH2AX staining. Globally, these cells presented transcriptional changes in cell cycle and senescence pathways." (https://www.biorxiv.org/content/10.1101/2022.02.22.481471v1.full?fbclid=IwAR3dj3Cp9En_8tchvFzoHADR6zT2eVgvQARlmnxALkKulyK68Zh0fhLZ6nM)
"However, with respect to the phenotype of 222-UVC-irradiated plants, the leaves curled under 1 kJ m−2 and were markedly bleached under 10 kJ m−2 compared with those of plants irradiated with 254-UVC... 222-UVC (1 or 5 kJ m−2) severely damaged the guard cells within the epidermis, and YFP signals and chloroplast autofluorescence in guard cells within the epidermis exposed to 222-UVC (1 or 5 kJ m−2) were not detected compared with those in cells exposed to 254-UVC radiation... These results suggest that 222-UVC severely damages guard cells and epidermal cells and that such damage might have resulted in growth inhibition." (https://link.springer.com/article/10.1007/s43630-021-00123-w)
" In contrast, 222-UVC had a significant effect on the loss of motility of C. elegans. The sensory nervous system, which includes dopamine CEP and PVD neurons on the body surface, was severely damaged by 222-UVC, but not by the same dose of 254-UVC. Interestingly, increasing 254-UVC irradiation by about 10-fold causes similar damage to CEP neurons. These results suggest that 222-UVC is less penetrating, so energy transfer occurs more effectively in tissues near the surface, causing more severe damage than 254-UVC. (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0281162)

Study by Syracuse University and University of Central Florida into worker productivity and indoor air quality showing strong correlation between clean air environments and workflow output:

https://www.researchgate.net/publication/379674443_Impact_of_Indoor_Air_Quality_and_Multi-domain_Factors_on_Human_Productivity_and_Physiological_Responses_A_Comprehensive_Review

Study by University of Colorado - Boulder and Lawrence Berkeley National Laboratory into the effectiveness of 100% outdoor air exchange versus MERV13 and HEPA filter upgrades showing the best filtration upgrade options leading to ~10% decrease in viral particulates and a corresponding increase in energy use:

https://www.researchgate.net/publication/379674443_Impact_of_Indoor_Air_Quality_and_Multi-domain_Factors_on_Human_Productivity_and_Physiological_Responses_A_Comprehensive_Review

University of Tokyo study finding 267 nm being the most efficacious wavelength for pathogen irradiation, with all wavelengths between 254 and 280 nm being effective:

https://pubmed.ncbi.nlm.nih.gov/34183999/